Lifestyle: Discovery may lead to new diabetes treatment
The discovery of a molecule that can help insulin last longer in the body and work more efficiently at lowering blood sugar could lead to a new treatment for diabetes, a new study in mice suggests. Giving the animals the molecule lowered levels of insulin-degrading enzyme (IDE), which then raised insulin levels, the Harvard University researchers report. Much more investigation is needed, but the compound may one day help people with diabetes control their disease more effectively, according to the authors of the study published in the journal Nature. "This work validates a new potential target for the treatment of diabetes," study co-author David Liu, a professor of chemistry and chemical biology at Harvard, said in a university news release. "What we show is that inhibiting IDE in an animal can improve glucose tolerance under conditions that mimic the intake of a meal if you administer this compound beforehand." Insulin-based diabetes treatments include insul...